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You are here:Home » Antibodies » Antibodies-Protein C » Anti -Protein C

Anti -Protein C


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Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B
Protein C is a vitamin K dependent serine protease zymogen. Purified human activated protein C selectively destroys factors Va and VIII:C in human plasma and thus has an important anticoagulant role. Protein C deficiency has been associated with inherited thrombophilia. In its primary structure, protein C is similar to the prothrombin group of blood coagulation factors. It most closely resembles factor X.
Protein C is synthesized as a single chain; this precursor molecule is cleaved into a light chain and a heavy chain held together by a disulfide bond. The enzyme is then activated by thrombin, which cleaves a tetradecapeptide from the amino end of the heavy chain.
Catalog #P9102-31B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No9L599
ConcentrationAs reported
FormSupplied as a liquid, 50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenNative purified mouse Protein C.
SpecificityRecognizes mouse Protein C and activated Protein C (aPC) by ELISA. In Western blot, recognizes mouse Protein C but does not react with aPC. Does not cross react with human Protein C or aPC. Does not inhibit activated Protein C. Weak inhibition of Protein C activation.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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