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You are here:Home » Antibodies » Abs to Ubiquitin » Anti -Protein Gene Product 9.5, aa175-191 (PGP9.5, Ubiquitin CT Hydrolase L1, UCH, UCHL1, Ubiquitin thiolesterase, PARK5)

Anti -Protein Gene Product 9.5, aa175-191 (PGP9.5, Ubiquitin CT Hydrolase L1, UCH, UCHL1,
Ubiquitin thiolesterase, PARK5)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Guinea pig Serum IH
PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Protein gene product (PGP9.5) is a neuron specific protein, structurally and immunologically distinct from neuron specific enolase. The protein which has a molecular weight of 27kD was first identified by high resolution two dimensional PAGE. Standard immunohistochemical techniques have demonstrated the presence of PGP9.5 in neurons and nerve fibres at all levels of the central and peripheral nervous system, in many neuroendocrine cells, in segments of the renal tubules, in spermatogonia and Leydig cells of the testis, in ova and in some cells of both the pregnant and non-pregnant corpus luteum. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility.
Catalog #P9102-71C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGuinea pig
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid with 0.05% sodium azide.
PuritySerum
ImmunogenSynthetic peptide corresponding to amino acids 175-191 (ASSEDTLLKDAAKVCR) of human PGP9.5.
SpecificityRecognizes human Protein Gene Product 9.5. Species crossreactivity: rat and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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