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You are here:Home » Antibodies » Abs to Ubiquitin » Anti -PGP9.5, CT (Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, UCH-L1, Ubiquitin Thiolesterase L1, Neuron Cytoplasmic Protein 9.5, UCHL1)

Anti -PGP9.5, CT (Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, UCH-L1, Ubiquitin
Thiolesterase L1, Neuron Cytoplasmic Protein 9.5, UCHL1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
UCHL1 is a member of family of proteins that hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. The expression of UCHL1 is highly specific to neurons and to cell of the diffuse neuroendocrine system and their tumors. UCHL1 exhibits both and hydrolase and a ligase activity. The S18Y variant of UCHL1, that has reduced ligase activity, has been linked to susceptibility for Parkinson's disease.
Catalog #P9102-71N1
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:5000
Western Blot: 1:500-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human UCHL1.
SpecificityRecognizes human UCHL1. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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