Anti -Podoplanin (PDPN, Aggrus, Glycoprotein 36kD, Glycoprotein 36, gp36, GP38, HT1A-1, hT1alpha1, hT1alpha2, Lung Type-I Cell Membrane-associated Glycoprotein Isoform a, OTS8, OTS-8, PA2.26 Antigen, T1 alpha, T1A, TIA2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH |
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| Podoplanin is absent on blood endothelium and therefore this product is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumor lymphangiogenesis. | | | Catalog # | P9104-91 | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Frozen and paraffin): 0.75-2ug/ml | | Note: Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Use sodium citrate buffer, pH 6.0. | | Optimal dilution determined by the researcher. | | Recommended Secondary Reagents | I1904-65W: IgG, F(ab’)2 (HRP) Pab RbxMo | | I1904-66C: IgG, F(ab’)2, X-Adsorbed (HRP) Pab RbxMo | | Recommended Negative Control | I1904-78R: IgG1 Murine Negative Control | | Recommended Positive Control Tissue | Normal lung | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 6A457 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | ORF Human podoplanin ectodomaine expressed in E. coli. | | Specificity | Recognizes Human Podoplanin (gp36), a 36kD type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Podoplanin (PDPN, Aggrus, Glycoprotein 36kD, Glycoprotein 36, gp36, GP38, HT1A-1, hT1alpha1, hT1alpha2, Lung Type-I Cell Membrane-associated Glycoprotein Isoform a, OTS8, OTS-8, PA2.26 Antigen, T1 alpha, T1A, TIA2) |
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