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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -Podoplanin (PDPN, Aggrus, Glycoprotein 36kD, Glycoprotein 36, gp36, PA2.26 Antigen, T1-alpha, T1A, PSEC0003, PSEC0025) (Biotin)

Anti -Podoplanin (PDPN, Aggrus, Glycoprotein 36kD, Glycoprotein 36, gp36, PA2.26 Antigen,
T1-alpha, T1A, PSEC0003, PSEC0025) (Biotin)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Affinity Purified B
Podoplanin, also called PA2.26 antigen, gp38, aggrus or T1a, is a type1 transmembrane sialomucin-type glycoprotein. It is specifically expressed by lymphatic endothelial cells but not blood vascular endothelial cells. Various carcinoma cells, as well as epithelial cells, keratinocytes and neuronal cells can also express the protein. Podoplanin is involved in cell adhesion and motility. The sialylated o-glycans on Podoplanin have been found to be required for Podoplanin-induced platelet aggregation. As a consequence of alternative splicing, an alternative isoform for human Podoplanin has been reported. Within the sequence included in this immunogen, human podoplanin shares 32% aa sequence identity with mouse podoplanin.
Catalog #P9104-91K
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 0.1-0.2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile TBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, 50ug/1ug BSA. Labeled with Biotin. Reconstitute with sterile TBS, pH 7.3, 20mM Trizma, 150mM sodium chloride, 0.1% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenNS0-derived rhPodoplanin isoform 1 extracellular domain.
SpecificityRecognizes human Podoplanin extracellular domain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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