Anti -Podoplanin (PDPN, Aggrus, Glycoprotein 36kD, Glycoprotein 36, gp36, PA2.26 Antigen,
T1-alpha, T1A, PSEC0003, PSEC0025) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
B |
|
| Podoplanin, also called PA2.26 antigen, gp38, aggrus or T1a, is a type1 transmembrane sialomucin-type glycoprotein. It is specifically expressed by lymphatic endothelial cells but not blood vascular endothelial cells. Various carcinoma cells, as well as epithelial cells, keratinocytes and neuronal cells can also express the protein. Podoplanin is involved in cell adhesion and motility. The sialylated o-glycans on Podoplanin have been found to be required for Podoplanin-induced platelet aggregation. As a consequence of alternative splicing, an alternative isoform for human Podoplanin has been reported. Within the sequence included in this immunogen, human podoplanin shares 32% aa sequence identity with mouse podoplanin. | | | Catalog # | P9104-91K | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilutions | Western Blot: 0.1-0.2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile TBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder from PBS, 50ug/1ug BSA. Labeled with Biotin. Reconstitute with sterile TBS, pH 7.3, 20mM Trizma, 150mM sodium chloride, 0.1% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | NS0-derived rhPodoplanin isoform 1 extracellular domain. | | Specificity | Recognizes human Podoplanin extracellular domain. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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