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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -PPP1R1A (Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, IPP1)

Anti -PPP1R1A (Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor
1, I-1, IPP-1, IPP1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
IPP-1 is a type 1 serine/threonine specific protein phosphatase inhibitor belonging to the protein phosphatase inhibitor 1 family. IPP-1 has multiple domains that target cellular PP1 complexes and establishes it as a cellular regulator of eIF2alpha phosphorylation. IPP-1 becomes active only after phosphorylation of a threonine residue by cAMP-dependent protein kinase. It is a selective inhibitor of protein phosphatase-1 (PP1) and regulates several PP1-dependent signaling pathways, including cardiac contractility and regulation of learning and memory. It is a widely expressed regulatory protein known to play an important role in hormonal control of glycogen metabolism.
Catalog #P9107-11J
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa50-100 from human PPP1R1A (KLH).
SpecificityRecognizes human PPP1R1A. Species sequence homology: Bovine, chimpanzee, canine, xenopus, equine, monkey, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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