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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -PPP2CA (Protein Phosphatase 2, catalytic subunit, alpha isozyme, PP2A-alpha, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform)

Anti -PPP2CA (Protein Phosphatase 2, catalytic subunit, alpha isozyme, PP2A-alpha, PP2Ac,
PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in the 5' UTR of this gene may cause a rare form of autosomal dominant spinocerebellar ataxia 12.
Catalog #P9107-34R1
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormTris-citrate/phosphate buffer, pH 7 to 8
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized maps to a region between residue 260 and the C-terminus (residue 309) of human Protein Phosphatase 2A (PPP2CB, Protein Phosphatase 2, Catalytic Subunit, Beta isoform) using the numbering given in entry NP_004147.1 (GeneID 5516). The region is identical to that of PPP2CA (NP_002706.1; GeneID: 5515).
SpecificitySpecies Crossreactivity: Human and mouse. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesProtein Phosphatase 2 Catalytic Subunit beta Isoform


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