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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -PPP2R4 (Serine/Threonine-protein Phosphatase 2A Activator, PP2A, Subunit B', PR53 Isoform, Phosphotyrosyl Phosphatase Activator, PTPA, Serine/Threonine-protein Phosphatase 2A Regulatory Subunit 4, Serine/Threonine-protein Phosphatase 2A Regulatory Subunit

Anti -PPP2R4 (Serine/Threonine-protein Phosphatase 2A Activator, PP2A, Subunit B', PR53
Isoform, Phosphotyrosyl Phosphatase Activator, PTPA, Serine/Threonine-protein Phosphatase
2A Regulatory Subunit 4, Serine/Threonine-protein Phosphatase 2A Regulatory Subunit

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B
Serine/threonine protein phosphatase 2A regulatory subunit 4 (PPP2R4) is one of the constituents of the regulatory subunit B' of PP2A (1). PPP2R4 is also known as the phosphatase activator (PTPA) and known to have the peptidyl prolyl isomerase (PPIase) activity (2-3). PPIases catalyze cis-trans isomerization of peptide bonds of proline residues in the polypeptide chain; this leads to the rapid folding of proteins (2). The ATPase activity of PPP2R4 is required for the phosphotyrosyl phosphatase activity of PP2A (2-4). Evidence suggests that PPP2R4 induces apoptosis independent of the canonical PP2A-mediated pathways (4).
Catalog #P9107-48A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No5G3
HostMouse
SourceMouse
ConcentrationNot determined
FormSupplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, <0.02% sodium azide, 50% glycerol.
PurityAscites
ImmunogenRecombinant protein specific to the mouse PPP2R4.
SpecificityRecognizes endogenous levels of total mouse PPP2R4. Species Crossreactivity: Human and monkey. Does not cross-react with other PP2A proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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