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You are here:Home » Antibodies » Antibodies-Enzymes, Phosphatase » Anti -PPP4C (Serine/Threonine Protein Phosphatase 4 Catalytic Subunit, PP4C, Pp4, Protein Phosphatase X, PP-X, PPP4, PPX)

Anti -PPP4C (Serine/Threonine Protein Phosphatase 4 Catalytic Subunit, PP4C, Pp4, Protein
Phosphatase X, PP-X, PPP4, PPX)


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Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Protein phosphatase 4 (protein phosphatase X) is a 35kD serine/threonine phosphatase with predicted binding sites for iron and manganese. It is found in both the cytoplasm and the nucleus. The phophoprotein alpha 4 has been identified as a potential regulatory subunit. PPP4C has been shown to localize to centrosomes/spindle pole bodies and is believed to be involved in microtubule organization. It may also play a role in relaying the TNF-alpha signal to the JNK pathway. Additionally, it has been shown to associate with C-Rel, NF-Kappa B p50, and RelA. Hence, it may be involved in the activation of these key mediators of immune response and apoptosis.
Catalog #P9107-51J
ApplicationsSuitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.1-0.3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in TBS, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-PQETRGIPSKKP of human PPP4C.
SpecificityRecognizes human PPP4C. Species sequence homology: bovine, canine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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