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Anti -PPP4C (Serine/Threonine Protein Phosphatase 4 Catalytic Subunit, PP4C, Pp4, Protein Phosphatase X, PP-X, PPP4, PPX)
Anti -PPP4C (Serine/Threonine Protein Phosphatase 4 Catalytic Subunit, PP4C, Pp4, Protein
Phosphatase X, PP-X, PPP4, PPX)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B IH |
|
| Protein phosphatase 4 (protein phosphatase X) is a 35kD serine/threonine phosphatase with predicted binding sites for iron and manganese. It is found in both the cytoplasm and the nucleus. The phophoprotein alpha 4 has been identified as a potential regulatory subunit. PPP4C has been shown to localize to centrosomes/spindle pole bodies and is believed to be involved in microtubule organization. It may also play a role in relaying the TNF-alpha signal to the JNK pathway. Additionally, it has been shown to associate with C-Rel, NF-Kappa B p50, and RelA. Hence, it may be involved in the activation of these key mediators of immune response and apoptosis. | | | Catalog # | P9107-51J | | Applications | Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.1-0.3ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-PQETRGIPSKKP of human PPP4C. | | Specificity | Recognizes human PPP4C. Species sequence homology: bovine, canine and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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