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Abs to Enzymes, Phosphatase
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Anti -PPP4C (Serine/Threonine Protein Phosphatase 4 Catalytic Subunit, PP4C, Pp4, Protein Phosphatase X, PP-X, PPP4, PPX)
Anti -PPP4C (Serine/Threonine Protein Phosphatase 4 Catalytic Subunit, PP4C, Pp4, Protein Phosphatase X, PP-X, PPP4, PPX)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
B IH |
|
| Protein phosphatase 4 (protein phosphatase X) is a 35kD serine/threonine phosphatase with predicted binding sites for iron and manganese. It is found in both the cytoplasm and the nucleus. The phophoprotein alpha 4 has been identified as a potential regulatory subunit. PPP4C has been shown to localize to centrosomes/spindle pole bodies and is believed to be involved in microtubule organization. It may also play a role in relaying the TNF-alpha signal to the JNK pathway. Additionally, it has been shown to associate with C-Rel, NF-Kappa B p50, and RelA. Hence, it may be involved in the activation of these key mediators of immune response and apoptosis. | | | Catalog # | P9107-51K | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Bovine | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.08% sodium azide. | | Purity | Purified | | Immunogen | Synthetic peptide corresponding to aa294-307 of bovine PPP4C (KLH). | | Specificity | Recognizes bovine PPP4C. Species sequence homology: Mouse, human and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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