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You are here:Home » Molecular Biology » MB-Enzymes, Phosphatase » Protein Tyrosine Phosphatase IA2, Catalytic Domain, aa693-979 (Protein Tyrosine Phosphatase Receptor type N, PTPRN, PTPIA2, Receptor-type Tyrosine-protein Phosphatase-like N, PTP IA-2, ICA512, IA2, R-PTP-N), Recombinant, Human

Protein Tyrosine Phosphatase IA2, Catalytic Domain, aa693-979 (Protein Tyrosine
Phosphatase Receptor type N, PTPRN, PTPIA2, Receptor-type Tyrosine-protein
Phosphatase-like N, PTP IA-2, ICA512, IA2, R-PTP-N), Recombinant, Human

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Specifications

Pseudophosphatase PTP-IA2, ICA-512), Catalytic domain, (a.a. 693- 979), (Genbank accession# NM_002846), with N-terminal GST tag, MW=58.8kD, expressed in an E. coli expression system.
Catalog #P9109-13
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
ApplicationSuitable for use as an immunogen, in binding assays or as an antigen in autoimmune assays.
Recommended DilutionOptimal dilution to be determined by researcher.
Storage and StabilityStore at -70°C. Aliquots are stable for at least 6 months at -70°C. Avoid repeated freeze-thaw cycles. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight58.8kD
SourceE. coli
Purity>95% by SDS-PAGE.
Concentration~0.4mg/ml
FormSupplied as a liquid in 25 Mm Tris-HCl, pH 8.0, 75 mM sodium chloride, 0.05% Tween-20, 50% glycerol, 2mM EDTA, 1mM DTT and 10 mM glutathione.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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