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Abs to Enzymes, Phosphatase
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Anti -PTPN6, CT (Tyrosine-protein Phosphatase Non-receptor Type 6, Protein-tyrosine Phosphatase 1C, PTP-1C, Hematopoietic Cell Protein-tyrosine Phosphatase, SH-PTP1, Protein-tyrosine Phosphatase SHP-1, HCP, PTP1C)
Anti -PTPN6, CT (Tyrosine-protein Phosphatase Non-receptor Type 6, Protein-tyrosine Phosphatase 1C, PTP-1C, Hematopoietic Cell Protein-tyrosine Phosphatase, SH-PTP1, Protein-tyrosine Phosphatase SHP-1, HCP, PTP1C)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E B |
|
| PTPN6 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. | | | Catalog # | P9109-22 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by ammonium sulfate precipitation. | | Immunogen | Synthetic peptide selected from the C-terminal region of human PTPN6 (KLH). | | Specificity | Recognizes human PTPN6. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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