Anti -PTPN13 (Tyrosine-protein Phosphatase Non-receptor Type 13, Fas-associated
Protein-tyrosine Phosphatase 1, FAP-1, PTP-BAS, Protein-tyrosine Phosphatase 1E, PTP-E1,
hPTPE1, Protein-tyrosine Phosphatase PTPL1, PNP1, PTP1E, PTPL1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E IH |
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| This protein is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as IkappaBalpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. | | | Catalog # | P9109-29S | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa2451-2466 of human PTPN13 (KLH). | | Specificity | Recognizes human PTPN13. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -PTPN13 (Tyrosine-protein Phosphatase Non-receptor Type 13, Fas-associated Protein-tyrosine Phosphatase 1, FAP-1, PTP-BAS, Protein-tyrosine Phosphatase 1E, PTP-E1, hPTPE1, Protein-tyrosine Phosphatase PTPL1, PNP1, PTP1E, PTPL1) |
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