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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -PRA1, CT (Prenylated Rab Acceptor)

Anti -PRA1, CT (Prenylated Rab Acceptor)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP FC
PRA1 (prenylated Rab acceptor) is a general regulator of Rab proteins. It has been shown that PRA1 interacts with Rab proteins and with VAMP2. Therefore PRA1 is probably an important factor for membrane traffic, linking together the function of Rab proteins and SNAREs. Human cells contain more than 60 small G proteins of the Rab family, which are localized to the surfaces of distinct membrane compartments and regulate transport vesicle formation, motility, docking and fusion. Prenylated Rabs also occur in the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which binds to Rabs in their inactive state.
Catalog #P9109-49
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation. Other applications not tested.
Recommended DilutionsWestern Blot: 1:500-1:2000
Flow Cytometry: 1:100
Immunoprecipitation: 1:30
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E504
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS pH 7.4, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human PRA1.
SpecificityRecognizes human PRA1, CT. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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