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You are here:Home » Antibodies » Abs to Tumor Suppressors » Anti -pTEN, CT (Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and Dual-specificity Protein Phosphatase PTEN, Mutated in Multiple Advanced Cancers 1, Phosphatase and Tensin Homolog, MMAC1, TEP1)

Anti -pTEN, CT (Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and
Dual-specificity Protein Phosphatase PTEN, Mutated in Multiple Advanced Cancers 1,
Phosphatase and Tensin Homolog, MMAC1, TEP1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
PTEN (also named as MMAC1/TEP1) is a tumor suppressor gene. It encodes a phosphatase and tensin homolog in chromosome10q23 region. This protein is a dual-specificity protein phosphatase and highly conserved in different species with only a single aa difference between human and mouse. Mutations of pTEN have been associated with various tumors such as gliomas, prostate cancer, breast cancer, etc. Multiple phosphorylation sites at the C-terminus of pTEN are involved in pTEN protein stability and function.
Catalog #P9182-02Q
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-terminus of human pTEN.
SpecificityRecognizes human pTEN.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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