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You are here:Home » Antibodies » Abs to Tumor Suppressors » Anti -PTEN Tumor Suppressor Protein (PTEN, MMAC1, Phosphatase and Tensin Homolog, TEP1)

Anti -PTEN Tumor Suppressor Protein (PTEN, MMAC1, Phosphatase and Tensin Homolog, TEP1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IP IH IC
PTEN is a tumor suppressor protein located on human chromosome 10 that is often mutated in various types of advanced cancers. The PTEN protein exhibits protein phosphatase activity and can suppress the growth of glioma cells.
Catalog #P9182-07A
ApplicationsSuitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:100
Immunohistochemistry: 1:20-1:50 for acetone-fixed, fresh frozen tissue. Not effective for paraffin sections.
Immunoprecipitation: 1:10-1:20
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q295
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.6, containing sodium azide.
PurityPurified IgG
Immunogen10-amino acid peptide sequence near the C-terminus of human PTEN.
SpecificityRecognizes human PTEN and is specific for the C-terminus. Reactivity with human fibroblasts, breast epithelial and lung cancer cell lines has been confirmed by Western Blot and antibody specificity has been confirmed by peptide blocking studies. Species Crossreactivity: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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