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Anti -PTEN Tumor Suppressor Protein (MMAC1, Phosphatase and Tensin, TEP1)
Anti -PTEN Tumor Suppressor Protein (MMAC1, Phosphatase and Tensin, TEP1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IP IH IC |
|
| PTEN is a tumor suppressor protein located on human chromosome 10 that is often mutated in various types of advanced cancers. The PTEN protein exhibits protein phosphatase activity and can suppress the growth of glioma cells. | | | Catalog # | P9182-07A | | Applications | Suitable for use in Western Blot, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. Other applications have not been tested. | | Recommended Dilution | Western Blot: 1:100 | | Immunohistochemistry: 1:20-1:50 for acetone-fixed, fresh frozen tissue. Not effective for paraffin sections. Immunoprecipitation: 1:10-1:20 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2Q295 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.6, containing sodium azide. | | Purity | Purified IgG | | Immunogen | Anti-PTEN has been generated by immunization with a 10 amino acid peptide to a sequence near the C-terminus of PTEN. | | Specificity | Recognizes human PTEN and is specific for the C-terminus. Reactivity with human fibroblasts, breast epithelial and lung cancer cell lines has been confirmed by Western Blot and antibody specificity has been confirmed by peptide blocking studies. Species Crossreactivity: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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