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You are here:Home » Antibodies » Abs to Stem Cell Research » Anti -PUM2 (Pumilio 2, Pumilio Homolog 2, Pumilio-2, KIAA0235, PUMH2)

Anti -PUM2 (Pumilio 2, Pumilio Homolog 2, Pumilio-2, KIAA0235, PUMH2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
PUM2 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.
Catalog #P9196-80G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:4000
Western Blot: 1-3ug/ml, observed in human epstein-Barr virus immortilised lymphoblastoid lysates on ~110kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DQNRDLKQGDDDDSK, from human PUM2, at the internal region of the protein (NP_056132.1).
SpecificityRecognizes human PUM2. Species sequence homology: Bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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