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You are here:Home » Biochemicals » Biochem-Antibiotics » Puromycin Aminonucleoside (3'-Dimethylamino-3'-deoxyadenosine)

Puromycin Aminonucleoside (3'-Dimethylamino-3'-deoxyadenosine)

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Specifications

Puromycin aminonucleoside is a semi-synthetic derivative of puromycin lacking the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis but exhibits antitumor properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing expression of integrin expression in cultured glomerular epithelial cells..
Catalog #P9200-02
Source Streptomyces alboniger, Semi-synthetic
Apperance White powder
Solubility Soluble in water.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number58-60-6
Molecular FormulaC12H18N6O3
Molecular Weight294.3
SourceStreptomyces alboniger
Purity~98%
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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