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You are here:Home » Biochemicals » Biochem-Antibiotics » Puromycin Aminonucleoside (3'-Dimethylamino-3'-deoxyadenosine)

Puromycin Aminonucleoside (3'-Dimethylamino-3'-deoxyadenosine)


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Puromycin aminonucleoside is a semi-synthetic derivative of puromycin lacking the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis but exhibits antitumor properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing expression of integrin expression in cultured glomerular epithelial cells..
Catalog #P9200-02
Source Streptomyces alboniger, Semi-synthetic
Apperance White powder
Solubility Soluble in water.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number58-60-6
Molecular FormulaC12H18N6O3
Molecular Weight294.3
SourceStreptomyces alboniger
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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