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Anti -Pyk2, CT (CAKbeta, cdk-activating Protein Kinase beta
Anti -Pyk2, CT (CAKbeta, cdk-activating Protein Kinase beta
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IP |
|
| Proline rich ptoein tyrosine kinase (Pyk2) is a focal adhesion kinase (FAK) related protein kinase protein also known as cell adhesion kinase ß (CAKß), related adhesion focal tyrosine kinase (RAFTK), or calcium-dependent PTK (CADTK) (3.4). Highly expressed in the nervous system protein tyrosine kinase (Pyk2) is phosphorylated on the tyrosine residue by a variety of G-protein-coupled receptor & extracellular signals that increase the level of Ca+ intracellulary (1,2). Pyk2 and FAK which co-locolize with integrins (5), share the same overall structure with a highly conserved central catalytic domain, phosphorylation/docking sites for Src homology SH2 domain and proline-rich binding sites for SH3 (3). | | | Catalog # | P9400B | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500 | | Immunoprecipitation: 1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 6k339 | | Host | Rabbit | | Source | Rat | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris glycine, pH7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA. | | Purity | Supernatant | | Immunogen | A synthetic peptide corresponding to residues in C-terminus of rat Pyk2 | | Specificity | Recognizes rat PYK2. Species Crossreactivity: human. Does not crossreact with other FAK family members. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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