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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -Pyk2, CT (CAKbeta, cdk-activating Protein Kinase beta

Anti -Pyk2, CT (CAKbeta, cdk-activating Protein Kinase beta


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Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP
Proline rich ptoein tyrosine kinase (Pyk2) is a focal adhesion kinase (FAK) related protein kinase protein also known as cell adhesion kinase ß (CAKß), related adhesion focal tyrosine kinase (RAFTK), or calcium-dependent PTK (CADTK) (3.4). Highly expressed in the nervous system protein tyrosine kinase (Pyk2) is phosphorylated on the tyrosine residue by a variety of G-protein-coupled receptor & extracellular signals that increase the level of Ca+ intracellulary (1,2). Pyk2 and FAK which co-locolize with integrins (5), share the same overall structure with a highly conserved central catalytic domain, phosphorylation/docking sites for Src homology SH2 domain and proline-rich binding sites for SH3 (3).
Catalog #P9400B
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No6k339
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris glycine, pH7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
ImmunogenA synthetic peptide corresponding to residues in C-terminus of rat Pyk2
SpecificityRecognizes rat PYK2. Species Crossreactivity: human. Does not crossreact with other FAK family members.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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