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Q0965 Quinaldopeptin (Antibiotic BMY 28662, Antibiotic BU 3845T) CAS: 130743-07-6

Specifications
References
CAS Number
130743-07-6
Grade
Highly Purified
Molecular Formula
C62H78N14O14
Molecular Weight
1243.4
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
+4°C
Antibiotic BMY 28662, Antibiotic BU 3845T

Quinaldopeptin is a symmetrical cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA. It exhibits strong in vitro antimicrobial and cytotoxic activity and significantly prolonged the survival time of mice inoculated with a murine tumor. Quinaldopeptin also shows weak nematocidal activity and is related to the luzopeptins and sandramycin.

Solubility
Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.
Storage and Stability
Lyophilized powder may be stored at -20°C. Reconstitute with DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer..
Related to: Quinomycin A
Source
Amycolatopsis sp.
Purity
>95% by HPLC
Form
Supplied as a yellow powder.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Quinaldopeptin, a novel antibiotic of the quinomycin family. Toda S. et al. J. Antibiot. 1990, 43, 796. |2. Structure of actinotetraose hexatiglate, a unique glucotetraose from an actinomycete bacterium. |Rickards R.W. et al. J. Antibiot. 1998, 51, 1093.
USBio References
No references available
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