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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified E B

Catalog #	R0006-74
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms	3A, 3B, 3C, and 3D (1). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (3). Specifically, Rab3 s are thought to play a key role in presynaptic vesicle trafficking and priming (2).
Applications	Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1:1000
	Optimal dilutions to be determined by the researcher.
Recommended Control	Rat cortex lysate
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Rat
Concentration	Not determined
Form	Supplied as a liqud in 10mM Hepes, pH 7.5, 150mM sodium chloride, 0.1% BSA, 50% glycerol.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Synthetic peptide corresponding to aa residues from the N-terminal region of rat Rab 3 (KLH). Species Sequence Homology: human, mouse, Xenopus, and non-human primates.
Specificity	Recognizes rat Rab3 at ~27kD.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.