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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified B

Rab3 is a group of closely related GTP-binding proteins (Rab3A, Rab3B, Rab3C and Rab3D) involved in regulating membrane traffic. Rab3 proteins are expressed in high levels in the brain and endocrine tissues but are also found elsewhere. They are localised on exocytic vesicles and in the brain they cycle on and off synaptic vesicles in parallel with the release of neurotransmitters. Many functions have been proposed for the Rab3 proteins, from fusion to docking and the biogenesis of vesicles. They are thought to play an important role in presynaptic vesicle trafficking and priming.
Catalog #	R0006-74A
Applications	Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1:1,000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Rat
Concentration	As reported
Form	Supplied as a liquid in 10mM HEPES, pH7.5, 150mM sodium chloride, 0.09% sodium azide, 0.01% BSA, 50% glycerol.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Peptide corresponding to aa residues from the N-terminal region of rat Rab3 (KLH).
Specificity	Recognizes rat RAB3. Species sequence homology: Mouse, Primate, Xenopus, Human.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.