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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified B

Ras-related protein RAB25, is a 23kD (unglycosylated) member of the small GTPase superfamily and RAB family of proteins. Human RAB25 is 213aa in length. The mature chain runs from aa1-210 with residues 211-213 constituting a propeptide. Residues 10-174 are noted to be RAB11-like. RAB11a, RAB11b, and RAB25 are closely related RAB proteins that are differentially expressed. Human RAB25 shares 96aa sequence identity with mouse RAB25. Functionally, RAB25 is involved in the regulation of cell survival. Researchers have shown that RAB25 promotes invasive migration of cells and increases the rates and aggressiveness of breast and ovarian cancers. It is expressed in breast and ovarian tissues.
Catalog #	R0009-83C
Applications	Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1ug/ml
	Optimal dilutions to be determined by the researcher.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2B
Clone No	11n162
Host	Mouse
Source	Human
Concentration	Not determined
Form	Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
Purity	Purified by Protein A/G affinity chromatography.
Immunogen	Recombinant corresponding to aa1-195 from human RAB25 expressed in E. coli (P57735).
Specificity	Recognizes human RAB25. No cross-reactivity with recombinant human RAB5A, 10, 11A, 27A, or 27B.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.