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You are here:Home » Antibodies » Abs to Infectious Disease Rabies » Anti -Rabies

Anti -Rabies

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH IF
Rabies virus is a Lyssavirus that causes rabies in mammals. The virus is found in the saliva of infected animals and is mostly spread though bites. The virus then travels though the peripheral nervous system to the central nervous system. Once it reaches the brain it causes acute encephalitis. Symptoms include paralysis, cerebral dysfunction, anxiety, insomnia, confusion, anger, paranoia, terror and hallucination. The production of a large amount of saliva, the inability to speak or swallow and associated hydrophobia is also common in the later stages of the disease. The time between exposure to the virus and onset of symptoms can range from about 2 weeks to several months. Once symptoms appear, death is virtually inevitable. However, the disease can be effectively treated by post-exposure prophylaxis, through vaccination, provided this is done as soon as possible.
Catalog #R0012
ApplicationsSuitable for use in Immunofluorescence, Indirect ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Formalin-fixed paraffin embedded sections.
Optimal dilutions to be determined by the researcher.
TiterImmunofluorescence: >1x10e3 (Titer by Native BHK)
Indirect ELISA: 1.5x10e6 (Titer by Indirect ELISA)
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.    
Clone TypeMonoclonal
IsotypeIgG2a
Clone No1.B.456
HostMouse
Concentration~3mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein G chromatography.
ImmunogenPurified rabies virus
SpecificityRecognizes a glycoprotein of more than 20 different strains of rabies virus from 4 serogroups: CVS, Lagosbat, Mokola, Duwenhage were positive in neutralization reaction.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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