Anti -RAE1 (RAE1 (RNA Export 1 S. pombe) Homolog, RAE1 Homolog, Rae1 Protein Homolog, RAE1
RNA Export 1 Homolog, RNA Export 1, RNA Export 1 Homolog, dJ481F12.3, dJ800J21.1,
FLJ30608, Homolog of yeast Rae1 mRNA-associated Protein of 41kD, MGC117333, MGC126076, M
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. | | | Catalog # | R0485-50 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Hepatocarcinoma cell line HepG2 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide: C-NAAEELKPRNKK, representing the C-terminus region of the human protein according to NP_003601.1; NP_001015885.1. | | Specificity | Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse and Rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -RAE1 (RAE1 (RNA Export 1 S. pombe) Homolog, RAE1 Homolog, Rae1 Protein Homolog, RAE1 RNA Export 1 Homolog, RNA Export 1, RNA Export 1 Homolog, dJ481F12.3, dJ800J21.1, FLJ30608, Homolog of yeast Rae1 mRNA-associated Protein of 41kD, MGC117333, MGC126076, M |
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