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You are here:Home » Antibodies » Abs to RNA Processing » Anti -RAE1 (RAE1 (RNA Export 1 S. pombe) Homolog, RAE1 Homolog, Rae1 Protein Homolog, RAE1 RNA Export 1 Homolog, RNA Export 1, RNA Export 1 Homolog, dJ481F12.3, dJ800J21.1, FLJ30608, Homolog of yeast Rae1 mRNA-associated Protein of 41kD, MGC117333, MGC126076, M

Anti -RAE1 (RAE1 (RNA Export 1 S. pombe) Homolog, RAE1 Homolog, Rae1 Protein Homolog, RAE1
RNA Export 1 Homolog, RNA Export 1, RNA Export 1 Homolog, dJ481F12.3, dJ800J21.1,
FLJ30608, Homolog of yeast Rae1 mRNA-associated Protein of 41kD, MGC117333, MGC126076, M

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Catalog #R0485-50
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Positive Control Human Hepatocarcinoma cell line HepG2
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: C-NAAEELKPRNKK, representing the C-terminus region of the human protein according to NP_003601.1; NP_001015885.1.
SpecificitySpecies Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse and Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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