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RANK, Recombinant, Human (Receptor Activator of NFkB)
RANK, Recombinant, Human (Receptor Activator of NFkB)
Pricing
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| Human RANK (receptor activator of NF-KappaB), a soluble 20kD protein, comprising the full-length of the TNF-like extracellular domain of RANKL, is a member of the TNFR family, identified as a dentritic cell membrane protein. | | | Catalog # | R1075 | | Endotoxin | 0.1ng/ug (1EU/ug) | | Reconstitution | Reconstitute with sterile dH2O to a concentration of 0.1-1mg/ml. Solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. | | Biological Activity | Determined by its ability to induce osteoclast formation in RAW264.7 cells using a concentration range of 5.0-10.0 ng/ml | | The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC (peripheral blood mononuclear cells) is 10ng/ml. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile dH2O, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 20kD | | Source | Human, recombinant expressed in E. coli | | Purity | 98% by SDS-PAGE and HPLC analysis. | | Form | Supplied as a lyophilized powder in PBS, pH 7.6. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Receptor activator of NF-KappaB |
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