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You are here:Home » Antibodies » Abs to RANK » Anti -RANKL (TNFSF11)

Anti -RANKL (TNFSF11)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
RUNX2 is a member of the RUNX family of transcription factors and is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in RUNX2 have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Catalog #R1075-17A
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR4999
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human RUNX2.
SpecificityRecognizes human RUNX2. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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