Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Growth Factors, Cytokines » Growth Factors-RANK » sRANKL, Recombinant, Human (soluble RANK Ligand, Receptor Activator of NFkB Ligand)

sRANKL, Recombinant, Human (soluble RANK Ligand, Receptor Activator of NFkB Ligand)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Catalog #R1076-03A
SourceRecombinant corresponding to human sRANKL expressed in E. coli.
Molecular Weight~20kD (corresponding to the full length of the TNF-like extracellular domain)
Biological ActivityED50 <10ng/ml. The biological activity was determined by measuring the dose-dependent stimulation of IL-8 production by isolated human PBMC’s. sRANKL, also known as ODF, TRANCE and TNF superfamily member 11, is a member of the TNF ligand superfamily. The receptor for sRANKL is RANK (Receptor Activator of NF-KappaB), a member of the TNFR family identified as a dendritic cell membrane protein. sRANKL influences dendritic cells’ ability to stimulate T-cells.
Endotoxin ~0.1ng/ug
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~20kD
Purity~98% (SDS-PAGE, HPLC)
ConcentrationNot determined
FormSupplied as a lyophilized powder in 5mM Tris, pH 7.6, and 50mM sodium chloride. Reconstitute with sterile dH2O to 0.1-1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links