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RANTES, Recombinant, Human (Regulated on Activation, Normal T-cell Expressed and Secreted)
RANTES, Recombinant, Human (Regulated on Activation, Normal T-cell Expressed and Secreted)
Pricing
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| RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). | | | Catalog # | R1100-05 | | Recombinant human RANTES is a 7.8kD protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC-chemokines. | | Amino Acid Sequence | SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS | | Endotoxin | 0.1ng/ug (1EU/ug) | | Biological Activity | Determined by its ability to chemoattract human blood monocytes using a concentration range of 1-10ng/ml. | | Responding Cells (partial list) | Monocytes | | Concentration Range for most in vitro applications | 0.2-20ng/ml | | Reconstitution | Lyophilized RANTES is soluble in water and most aqueous buffers. Reconstitute in sterile dH2O to a concentration of 0.1-1mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile dH2O. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Country of Origin | USA | | Molecular Weight | 7.8kD | | Source | Human, recombinant expressed in E. coli | | Purity | 98% by SDS-PAGE and HPLC analyses. | | Form | Supplied as a lyophilized powder without additives. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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