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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified B

Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Catalog #	R1120-10
Recommended Dilutions	Western Blot (ECL): 1ug/ml detects Rap1 in 20ug of rat brain tissue extract.
	Optimal dilutions to be determined by the researcher.
Positive Controls	Rat and Mouse Brain Tissue Extract
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Human
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Synthetic peptide corresponding to a portion of human Rap1a. Peptide differs from Rap1b by two residues.
Specificity	Recognizes human Rap1 at ~25kD. Species Crossreactivity: mouse, rat, bovine, canine, chicken, guinea pig, hamster, monkey, porcine, rabbit, sheep and Xenopus.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.