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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -RAP2A (RAP2A Member of RAS Oncogene Family, Ras-related Protein Rap-2a, RAP2, KREV, K-REV, RbBP-30)

Anti -RAP2A (RAP2A Member of RAS Oncogene Family, Ras-related Protein Rap-2a, RAP2, KREV,
K-REV, RbBP-30)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
RAP2A is a signaling protein involved in small GTPase mediated signal transduction activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2, in a cAMP-dependent manner, and GFR. This membrane protein belongs to the small GTPase superfamily and Ras family and contains domains required for GTP binding and a Ras-like C-terminal motif for post-translational lipid binding and subsequent anchoring to the plasma membrane. Apart from having a possible role in membrane shedding, RAP2A also functions as a slowly responding molecular switch in the RAP1A signaling cascade and also interacts with ARHGAP29, the putative specific effector of RAP2A.
Catalog #R1120-60
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.1-0.3ug/ml
Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlMCF7 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa140-190 of human RAP2A.
SpecificityRecognizes human RAP2A. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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