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Abs to GTPase, Rab, Ras, Rho Proteins
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Anti -RAP2A (RAP2A Member of RAS Oncogene Family, Ras-related Protein Rap-2a, RAP2, KREV, K-REV, RbBP-30)
Anti -RAP2A (RAP2A Member of RAS Oncogene Family, Ras-related Protein Rap-2a, RAP2, KREV,
K-REV, RbBP-30)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| RAP2A is a signaling protein involved in small GTPase mediated signal transduction activated by guanine nucleotide-exchange factors (GEF) EPAC and EPAC2, in a cAMP-dependent manner, and GFR. This membrane protein belongs to the small GTPase superfamily and Ras family and contains domains required for GTP binding and a Ras-like C-terminal motif for post-translational lipid binding and subsequent anchoring to the plasma membrane. Apart from having a possible role in membrane shedding, RAP2A also functions as a slowly responding molecular switch in the RAP1A signaling cascade and also interacts with ARHGAP29, the putative specific effector of RAP2A. | | | Catalog # | R1120-60 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.1-0.3ug/ml | | Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | MCF7 cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa140-190 of human RAP2A. | | Specificity | Recognizes human RAP2A. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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