Anti -Ras, p21 (c-bas/has, c-H-ras, C-HA-RAS1, c-has/bas p21, CTLO, GTPase HRas, HAMSV,
Ha-Ras, HRAS, H-Ras, HRAS1, H-Ras-1, H-RASIDX, K-RAS, N-RAS, p21ras, RASH1, Transforming
Protein p21, v-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
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| H-Ras, otherwise known as p21Ras, a ubiquitously expressed lipid-anchored GTPase and member of the Ras superfamily of small GTPases, which acts as a molecular signal transduction on/off switch on the inner surface of the plasma membrane and endomembranes. H-Ras, N-Ras and K-Ras4A/4B are highly related RAS genes which regulate pathways involved in cell differentiation, proliferation, adhesion, migration and apoptosis and are known proto-oncogenes. Mutations in the H-Ras gene are responsible for the rare condition known as Costello syndrome characterized by facial, cardiovascular and musculoskeletal abnormalities and mental retardation. | | | Catalog # | R1198-01C | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10F13 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aaDIHQYREQIKRVKDSDDC of human H-Ras. | | Specificity | Recognizes human H-Ras, otherwise known as p21Ras. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Ras, p21 (c-bas/has, c-H-ras, C-HA-RAS1, c-has/bas p21, CTLO, GTPase HRas, HAMSV, Ha-Ras, HRAS, H-Ras, HRAS1, H-Ras-1, H-RASIDX, K-RAS, N-RAS, p21ras, RASH1, Transforming Protein p21, v-Ha-ras Harvey Rat Sarcoma Viral Oncogene Homolog) |
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