Anti -Ras, p21 (c-bas/has, c-H-Ras, c-has/bas p21, C-K-RAS, c-K-Ras2, c-Ki-Ras,
c-Kirsten-Ras, c-Ras Ki-2, G1III6 N-Ras, GTPase HRas KRas NRas, H-Ras-1, H-RasIDX, Ha-Ras,
HRAS, HRAS1, K-Ras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Kirsten Rat Sarcoma 2 Vi
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IP FC |
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| Ras (p21), a signal transducer, was first characterized as the transforming genes of Harvey & Kristen sarcoma virus (1). The Ras family (H-Ras, N-Ras, and K-Ras) regulates cell growth, differentiation and apoptosis (2). Switching from an active or resting state, Ras can either bind GTP or GDP respectively. In the triphosphate conformation, Ras will interact with GTPase activating protein (GAP) to increase its activity (3). Mutations in any of the three isoforms can convert these proteins into active oncogenes. Additionally, Ras mutations are found in 30% of all human cancer (4). | | | Catalog # | R1198-01L | | Applications | Suitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:100 | | Western Blot: 1:1000-1:10,00 | | Immunoprecipitation: 1:30 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9C39 | | Host | Rabbit | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.01% sodium azide, 0.05% BSA, 40% glycerol. | | Purity | Ascites | | Immunogen | A synthetic peptide corresponding to residues near the N-terminal region of human Ras. | | Specificity | Recognizes human H-Ras, N-Ras and K-Ras. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Ras, p21 (c-bas/has, c-H-Ras, c-has/bas p21, C-K-RAS, c-K-Ras2, c-Ki-Ras, c-Kirsten-Ras, c-Ras Ki-2, G1III6 N-Ras, GTPase HRas KRas NRas, H-Ras-1, H-RasIDX, Ha-Ras, HRAS, HRAS1, K-Ras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Kirsten Rat Sarcoma 2 Vi |
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