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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -Ras, p21 (c-bas/has, c-H-Ras, c-has/bas p21, C-K-RAS, c-K-Ras2, c-Ki-Ras, c-Kirsten-Ras, c-Ras Ki-2, G1III6 N-Ras, GTPase HRas KRas NRas, H-Ras-1, H-RasIDX, Ha-Ras, HRAS, HRAS1, K-Ras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Kirsten Rat Sarcoma 2 Vi

Anti -Ras, p21 (c-bas/has, c-H-Ras, c-has/bas p21, C-K-RAS, c-K-Ras2, c-Ki-Ras,
c-Kirsten-Ras, c-Ras Ki-2, G1III6 N-Ras, GTPase HRas KRas NRas, H-Ras-1, H-RasIDX, Ha-Ras,
HRAS, HRAS1, K-Ras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Kirsten Rat Sarcoma 2 Vi

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP FC
Ras (p21), a signal transducer, was first characterized as the transforming genes of Harvey & Kristen sarcoma virus (1). The Ras family (H-Ras, N-Ras, and K-Ras) regulates cell growth, differentiation and apoptosis (2). Switching from an active or resting state, Ras can either bind GTP or GDP respectively. In the triphosphate conformation, Ras will interact with GTPase activating protein (GAP) to increase its activity (3). Mutations in any of the three isoforms can convert these proteins into active oncogenes. Additionally, Ras mutations are found in 30% of all human cancer (4).
Catalog #R1198-01L
ApplicationsSuitable for use in Flow Cytometry, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:100
Western Blot: 1:1000-1:10,00
Immunoprecipitation: 1:30
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9C39
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.01% sodium azide, 0.05% BSA, 40% glycerol.
PurityAscites
ImmunogenA synthetic peptide corresponding to residues near the N-terminal region of human Ras.
SpecificityRecognizes human H-Ras, N-Ras and K-Ras. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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