Anti -RasGAP (RAS p21 protein activator (GTPase activating protein) 1, CMAVM, CM-AVM,
DKFZp434N071, GAP, GTPase-activating protein, p120GAP, p120RASGAP, PKWS, RASA1, RASGAP,
Ras GTPase-activating protein 1, Ras p21 protein activator)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IC |
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| Ras-GTPase-activating protein SH3-domain-binding protein; GAP binding protein; RasGAP-associated endoribonuclease G3BP: This protein is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. | | | Catalog # | R1198-11 | | Applications | Suitable for use in Western Blot, Immunoprecipitation, and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Immunoprecipitation: 2.5ug. Immunoprecipates RasGAP from 500ug of A431 cell lysate. | | Western Blot: 0.5-2ug/ml. Detects GAP in 10ug of A431 cell lysate. | | Immunocytochemistry: 10ug/ml. Detects RasGAP on A431 cells fixed with ethanol acetic acid (50:50). | | Optimal dilutions to be determined by the researcher. | | Positive Antigen Control | A0001-50A: A431 Cells, Non-Stimulated in RIPA Buffer, w/o Sample Buffer | | Storage and Stability | Lyophilized powder may be stored at -20°C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Also Available Ras Products | Enzymes: | | R0495-15: Raf 1 RBD, Recombinant, Human (Agarose) | | R1198-20: Ras, GST (Agarose) | | Antibodies | R1198: Ras, p21, N,H,K Mab Mo xHu | | Kits | R1198-07: Ras Activation Assay Kit, BioAssay™ | | Ha-Ras Products | Antibodies: | | R1198-34: Ras, H (Harvey Murine Sarcoma Virus Oncogene, Ha-Ras) Mab Rb xHu | | RasGAP Products | Antibodies: | | R1198-11: Ras, GAP (Ras GTPase Activating Protein, GAP) Mab Mo xHu | | R1198-12: Ras, GAP (Ras GTPase Activating Protein, GAP) Pab Rb xHu | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 0.T.131 | | Host | Mouse | | Source | Human | | Form | Supplied as a lyophilized powder in Tris-glycine, pH 7.2, containing sodium azide. Reconstitute with sterile 40-50% glycerol, ddH2O. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Full length recombinant human RasGAP expressed in sf9 insect cells. | | Specificity | Specific for human RasGAP (120kD). Species Crossreactivity: rat, mouse, hamster and bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -RasGAP (RAS p21 protein activator (GTPase activating protein) 1, CMAVM, CM-AVM, DKFZp434N071, GAP, GTPase-activating protein, p120GAP, p120RASGAP, PKWS, RASA1, RASGAP, Ras GTPase-activating protein 1, Ras p21 protein activator) |
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