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Abs to GTPase, Rab, Ras, Rho Proteins
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Anti -RasGAP (Ras GTPase-activating Protein 1, GAP, GTPase-activating Protein, Ras p21 Protein Activator, p120GAP, RASA1, RASA)
Anti -RasGAP (Ras GTPase-activating Protein 1, GAP, GTPase-activating Protein, Ras p21
Protein Activator, p120GAP, RASA1, RASA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH |
|
| The mammalian proto-oncogene Ras encodes 21kD proteins (p21Ras) which exists in either a physiologically quiescent GDP-binding state or a GTPbinding signal-emitting state. Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold. The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity. | | | Catalog # | R1198-12A | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-4ug/ml | | Immunoprecipitation: 10-20ug/ml | | Immunohistochemistry: 10-20ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1025 from human RasGAP. | | Specificity | Recognizes human RasGAP at ~120kD. Species Crossreactivity: mouse, rat and bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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