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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -RASA4 (CAPRI, Ras GTPase-activating Protein 4, Calcium-promoted Ras Inactivator, Ras p21 Protein Activator 4, RasGAP-activating-like Protein 2, GAPL, KIAA0538)

Anti -RASA4 (CAPRI, Ras GTPase-activating Protein 4, Calcium-promoted Ras Inactivator, Ras
p21 Protein Activator 4, RasGAP-activating-like Protein 2, GAPL, KIAA0538)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Catalog #R1200-11N
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Liver lysates
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to AKRSSLYIRIVEGC, from the N-terminus of the protein sequence according to NP_008920.
SpecificityRecognizes CAPRI. Species sequence homology: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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