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Abs to GTPase, Rab, Ras, Rho Proteins
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Anti -RASA4 (CAPRI, Ras GTPase-activating Protein 4, Calcium-promoted Ras Inactivator, Ras p21 Protein Activator 4, RasGAP-activating-like Protein 2, GAPL, KIAA0538)
Anti -RASA4 (CAPRI, Ras GTPase-activating Protein 4, Calcium-promoted Ras Inactivator, Ras
p21 Protein Activator 4, RasGAP-activating-like Protein 2, GAPL, KIAA0538)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. | | | Catalog # | R1200-11N | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Liver lysates | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to AKRSSLYIRIVEGC, from the N-terminus of the protein sequence according to NP_008920. | | Specificity | Recognizes CAPRI. Species sequence homology: human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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