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Specifications

Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. It displays a selective antitumour activity against several cell lines. Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II. Analogues of rebecamycin are currently in several clinical trials for cancer therapy.
Catalog #	R1281-15
Purity	>99% by HPLC
Solubility	Soluble in THF or DMSO. Poorly soluble in methanol and water.
Related to	Staurosporine, Antibiotic UCN-01, Antibiotic UCN-02
CAS Number	93908-02-2
Molecular Formula	C27H21Cl2N3O7
Molecular Weight	570.4
Source	Lechevalieria sp.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.