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You are here:Home » Biochemicals » Biochem-Antibiotics » Rebeccamycin



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Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. It displays a selective antitumour activity against several cell lines. Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II. Analogues of rebecamycin are currently in several clinical trials for cancer therapy.
Catalog #R1281-15
Purity >99% by HPLC
Solubility Soluble in THF or DMSO. Poorly soluble in methanol and water.
Related to Staurosporine, Antibiotic UCN-01, Antibiotic UCN-02
CAS Number93908-02-2
Molecular FormulaC27H21Cl2N3O7
Molecular Weight570.4
SourceLechevalieria sp.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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