Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Antibodies-Extracellular Matrix Proteins » Anti -Reelin (RELN, RL, Reeler)

Anti -Reelin (RELN, RL, Reeler)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP IH IF
Reelin is a 400kD, extracellular matrix glycoprotein secreted by several neurons. It is a serine protease that degrades fibronectin and laminin. Reelin also binds lipoprotein receptor superfamily members APOER2 and VLDLR which transduce signals important for neuronal positioning during brain development and synaptic plasticity in the adult brain. In vivo, Reelin undergoes proteolytic processing at two sites, generating three Reelin fragments. The central fragment is sufficient for binding and signaling via the lipoprotein receptors. Three isoforms of mouse Reelin that differ in their C-terminal fragments have been described. Within its central regions, mouse reelin shares 95% and 98% amino acid sequence identity with human and rat reelin, respectively
Catalog #R1362-01
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionsWestern Blot: 1:250-1:1000
Immunoprecipitation: 1:10-1:500
Immunohistochemistry (Paraffin): 1:250-1:500
Immunohistochemistry: 1:10-1:2000
Immunofluorescence (IC): 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlIHC labeling of Cajal-Retzius cells in the embryonic mouse telencephalon.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No9C51
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa164-189 of Reelin (NM_005045.2). Cellular Localization: Secreted
SpecificityRecognizes Reelin. Expected to react with a wide range of species.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links