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You are here:Home » Antibodies » Abs to Oncoproteins » Anti -REL (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel)

Anti -REL (C-Rel Proto-oncogene Protein, C-Rel protein, Proto-oncogene c-Rel)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
Catalog #R1423-50J
NF-kB (nuclear factor kB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. In most cells, inhibitory IkB proteins sequester NF-kB/Rel in the cytoplasm. Cellular stimulation results in the degradation of IkB and modification of NF-kB/Rel proteins, allowing NF-kBRel (c-Rel and RelA) to translocate to the nucleus and act on its target genes.
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:5000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide, glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa10-28 (IEIIEQPRQRGMRFRYKCE) of human c-Rel. (Genbank: NP_002899.)
SpecificityRecognizes human c-Rel. Species sequence homology: chicken, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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