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Resistin, Recombinant, Mouse (ADSF, Adipose Tissue-Specific Secretory Factor, FIZZ3, Found in Inflammatory Zone)
Resistin, Recombinant, Mouse (ADSF, Adipose Tissue-Specific Secretory Factor, FIZZ3, Found
in Inflammatory Zone)
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| Resistin, otherwise known as adipose tissue-specific secretory factor, is an adipose-derived hormone and member of the resistin/FIZZ family, implicated as a suppressor of the ability of insulin to reduce blood sugar, and to play a role in type 2 diabetes and obesity. Studies have shown that resistin is involved in an increase in the transcription/expression of many pro-inflammatory cytokines, including interleukin-1,-6 and -12, and also upregulates vascular cell-adhesion molecule-1 (VCAM-1), intracellular adhesion molecule-1 (ICAM-1), and monocyte chemotactic protein-1 (MCP-1/CCL2). | | | Catalog # | R1585-05A | | Source | E. coli | | Applications | Suitable for use in Functional Assays. Other applications not tested. | | Endotoxin | 1EU/ug | | Molecular Weight | 20.2kD (94 amino acid residue homodimer) | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | E. coli | | Purity | 98% (SDS PAGE and HPLC). | | Concentration | ~0.1mg/ml | | Form | Supplied as a lyophilized powder. Reconstitute with 250ul sterile dH20. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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