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You are here:Home » Antibodies » Abs to Resistin » Anti -Resistin (ADSF, Adipose Tissue-Specific Secretory Factor, FIZZ3, Found in Inflammatory Zone)

Anti -Resistin (ADSF, Adipose Tissue-Specific Secretory Factor, FIZZ3, Found in
Inflammatory Zone)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family (Resistin, RELM-alpha and RELM-beta) share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake. It is postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant human Resistin is a 19.5kD disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond.
Catalog #R1585-09P
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA (Direct and indirect): 1:5000-1:10,000
Western Blot: 1:2000-1:10,000 (ECL); Suggested blocking and dilution buffer is TBST containing 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at RT.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG2a
Clone No6D730
HostMouse
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4. No preservative added.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant rat resistin.
SpecificityRecognizes both natural and recombinant rat resistin. Detects a band of ~10kD by Western Blot. Species Crossreactivity: Weakly crossreacts with human and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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