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Anti -Resistin, alpha, aa83-92 (ADSF, Adipose Tissue-Specific Secretory Factor, FIZZ3, Found in Inflammatory Zone)
Anti -Resistin, alpha, aa83-92 (ADSF, Adipose Tissue-Specific Secretory Factor, FIZZ3,
Found in Inflammatory Zone)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IC |
|
| Alpha resistin is a member of a family of proteins that are produced by adipose tissue and released into the circulation that has been linked to insulin resistance and dietary obesity. The protein has been shown to be regulated by the anti-diabetic thiazolidinedione class of drugs. | | | Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family, and is also described as ADSF (Adipose Tissue-Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone). Human resistin contains 108aa as a prepeptide, and its hydrophobic signal peptide is cleaved before its secretion. Resistin circulates in human blood as a dimeric protein consisting of two 92aa polypeptides, which are disulfide-linked via Cys26. | | | Resistin may be an important link between obesity and insulin resistance. Mouse resistin, specifically produced and secreted by adipocytes, acts on skeletal muscle myocytes, hepatocytes and adipocytes themselves so that it reduces their sensitivity to insulin. | | | Catalog # | R1585-35 | | Applications | Suitable for use in Immunoblot, Immunocytochemistry and ELISA. Other applications not tested. | | Recommended Dilution | Immunoblot: 1:250-1:500 | | Immunocytochemistry: 1:75-1:150 | | ELISA: 1:10,000 | | Optimal dilutions to be determined by the researcher. | | | | Storage and Stability: | | For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Mouse | | Concentration | As reported | | Form | Supplied as a liquid in 20mM PBS, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide from mouse alpha resistin (aa83-92) | | Specificity | Recognizes mouse alpha resistin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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