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Anti -Resistin-like Molecule, alpha (RELMa)
Anti -Resistin-like Molecule, alpha (RELMa)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| RELM-alpha/FIZZ1/PMNG1 (Parasite-induced Macrophage Novel Gene 1 (prepeptides: mouse/rat 111aa; ~77% identity) is 63% related to resistin at the C-terminus (38aa). The N-terminus of RELM-alpha is less conserved at the N-terminus. RELM-alpha mRNA was most abundant in white adipose tissue. It is also expressed in mammary tissue with significant fat pads. Unlike resistin, RELM-alpha is not expressed in 3T3-L1 adipocyte or in preadipocytes. It is also found in heart, lung and tongue, where resistin is absent. In mice, RELM-alpha/FIZZ1 is found at low levels in a subset of bronchial epithelial cells and in non-neuronal cells adjacent neurovascular bundles in the peribronchial stroma, and in the wall of the large and small bowel. FIZZ1 expression is induced hypertrophic, hyperplastic bronchial epithelium. | | | Catalog # | R1587-04 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilutions | Western Blot: 1-5ug/ml (ECL) | | ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well. | | Optimal dilutions to be determined by the researcher. | | Control Peptide | R1587-03: Resistin-like Molecule, alpha, Mouse, Control Peptide (RELMa) | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.1% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A synthetic peptide corresponding to 14aa near the N-terminus of mouse RELM-alpha. conjugated to KLH. | | Specificity | Recognizes mouse Resistin-like Molecule, alpha (RELMa). Species sequence homology: rat, 50%. No homology to human Resistin-like Molecule, alpha. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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