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You are here:Home » Antibodies » Abs to Resistin » Anti -Resistin-like Molecule, beta (RELMbeta, RELM-beta, RELMb, RETNLB, beta RELM, C/EBP epsilon Regulated Myeloid Specific Secreted Cysteine-rich Protein Precursor 2, Colon and Small Intestine-specific Cysteine-rich Protein, Colon Carcinoma-related Gene Protei

Anti -Resistin-like Molecule, beta (RELMbeta, RELM-beta, RELMb, RETNLB, beta RELM, C/EBP
epsilon Regulated Myeloid Specific Secreted Cysteine-rich Protein Precursor 2, Colon and
Small Intestine-specific Cysteine-rich Protein, Colon Carcinoma-related Gene Protei

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Ascites E B
RELM-alpha/FIZZ1/PMNG1 (Parasite-induced Macrophage Novel Gene 1 (prepeptides: mouse/rat 111aa; ~77% identity) is 63% related to resistin at the C-terminus (38aa). The N- terminus of RELM-alpha is less conserved at the N-terminus. RELM-alpha mRNA was most abundant in white adipose tissue. It is also expressed in mammary tissue with significant fat pads. Unlike resistin, RELM-alpha is not expressed in 3T3-L1 adipocyte or in preadipocytes. It is also found in heart, lung and tongue, where resistin is absent. FIZZ1 expression is induced hypertrophic, hyperplastic bronchial epithelium.
Catalog #R1587-21E
RELM-beta/FIZZ2 (prepeptides mouse 105aa; human 11aa ~45-65% identity with FIZZ1 and 2) is highly related to resistin at the C-terminus region. Its expression is most abundant in colon (proximal and distal colon) but not in white adipose tissue. In mouse, RELM-beta is also detected at low levels in cecum and ileum. In min mouse (mouse model for human familial adenomatosus polyposis), RELM-beta expression was markedly increased in tumors immediately adjacent to normal tissue.
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:10,000-1:100,000 (using 50-100ng control peptide/protein/well)
Western Blot: 1:1500-1:2,000 (ECL)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No11C147
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, 0.05% sodium azide.
PurityAscites
ImmunogenRecombinant purified mouse RELM-beta protein
SpecificityRecognizes mouse RELM-beta.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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