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You are here:Home » Biochemicals » Biochem-Antibiotics » Reticulol (6,8-Dihydroxy-7-methoxy-3-methylisocoumarin)

Reticulol (6,8-Dihydroxy-7-methoxy-3-methylisocoumarin)


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Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation mechanism. Reticulol has also been demonstrated to cause a dose dependent inhibition of lung metastasis in the B16F10 melanoma model.
Catalog #R1650-35
Purity >95% by HPLC
Solubility Soluble in ethanol, methanol, DMF or DMSO
CAS Number26246-41-3
Molecular FormulaC11H10O5
Molecular Weight222.2
SourceStreptomyces sp.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names6,8-Dihydroxy-7-methoxy-3-methylisocoumarin

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