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Reticulol (6,8-Dihydroxy-7-methoxy-3-methylisocoumarin)
Reticulol (6,8-Dihydroxy-7-methoxy-3-methylisocoumarin)
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| Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation mechanism. Reticulol has also been demonstrated to cause a dose dependent inhibition of lung metastasis in the B16F10 melanoma model. | | | Catalog # | R1650-35 | | Purity | >95% by HPLC | | Solubility | Soluble in ethanol, methanol, DMF or DMSO | | CAS Number | 26246-41-3 | | Molecular Formula | C11H10O5 | | Molecular Weight | 222.2 | | Source | Streptomyces sp. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin |
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