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You are here:Home » Antibodies » Abs to Myosin » Anti -RBBP8 (DNA Endonuclease RBBP8, CtBP-interacting Protein, CtIP, Retinoblastoma-binding Protein 8, RBBP-8, Retinoblastoma-interacting Protein and Myosin-like, RIM, Sporulation in the Absence of SPO11 Protein 2 Homolog, SAE2, CTIP)

Anti -RBBP8 (DNA Endonuclease RBBP8, CtBP-interacting Protein, CtIP,
Retinoblastoma-binding Protein 8, RBBP-8, Retinoblastoma-interacting Protein and
Myosin-like, RIM, Sporulation in the Absence of SPO11 Protein 2 Homolog, SAE2, CTIP)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by ensuring both resection and intrachromosomal association of the broken ends. Promotes ATR and RPA recruitment to DSBs in S/G2 phase and facilitates the generation of ssDNA. May modulate the functions ascribed to BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.
Catalog #R1665-38
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:10,000
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7, 0.01% thimerosal, 10% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to aa452-747 of human CtIP.
SpecificityRecognizes human RBBP8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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