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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -Retinoic Acid Receptor Responder 1 (RARRES1, Tig1)

Anti -Retinoic Acid Receptor Responder 1 (RARRES1, Tig1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
RARRES1 (retinoic acid receptor responder 1; also Tig1) is a member of the protease inhibitor I47 family of proteins. It is expressed in epithelium, including keratinocytes, plus prostate and breast epithelium. It is considered to be a tumor-suppressor molecule, presumably acting as an inhibitor of carboxypeptidase A. Human RARRES1 is 294aa in length. It is a type II transmembrane (TM) protein with a TM segment between aa21-42. Three potential splice variants exist. There is a 46aa N-terminal extension, a four aa substitution for aa225-294 and a combination of these two variants. Over aa43-294, human RARRES1 shares 75% aa identity with human RARRES1.
Catalog #R1691-98
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.5-1.0ug/ml
Western Blot: 1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human RARRES1 isoform 2 extracellular domain aa43-294; P49788 (E. coli)
SpecificityRecognizes human RARRES1 extracellular domain.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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