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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E B

RET protein is a member of the cadherin superfamily. It is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. RET protein plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in RET protein are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Catalog #	R1701-17
Applications	Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilutions	Optimal dilutions to be determined by the researcher.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG
Clone No	9G431
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
Purity	Purified by Protein G affinity chromatography.
Immunogen	Partial recombinant human RET protein (361-458) with a GST tag.
Specificity	Recognizes human RET protein. Species Crossreactivity: mouse and rat
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.