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You are here:Home » Antibodies » Abs to G Proteins » Anti -RGS13 (Regulator of G Protein Signaling 13, HGNC:9995, MGC17173)

Anti -RGS13 (Regulator of G Protein Signaling 13, HGNC:9995, MGC17173)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This protein is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
Catalog #R1996-26C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32000
Western Blot: 0.5-1.5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Peripheral Blood Mononucleocyte lysates
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide with sequence DESKRPPSNLTLEE-C, from the N-Terminus of human RGS13 (NP_658912.1).
SpecificityRecognizes human RGS13 at ~19kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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