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R1998-92 Rabbit Anti-Rhox-13 Reproductive Homeobox on X Chromosome 13, Reproductive Homeobox (Rhox) 13)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Mo
Shipping Temp
Blue Ice
Storage Temp
-20°C

The Rhox-13 protein is a reproductive homeobox protein found on the X chromosome. This transcription factor belongs to the homeobox gene family whose expression organizes programs of development. Reproductive homeobox genes regulate development of reproductive tissues including the testis, ovary, and placenta. Most of the Rhox genes are expressed in Sertoli cells, the nurse cells in direct contact with developing male germ cells. This suggests that they regulate the expression of somatic-cell gene products critical for germ cell development. Transcripts of this protein are found in the testis and ovary as early as 13.5Dys post coitum. Transcription ceases in the ovary threeDys post partum, but continues in the testis through adulthood.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 2-4ug/ml Optimal dilutions to be determined by the researcher.
Positive Control
Mouse Embryo Testis
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa1-50 of Rhox-13.
Form
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes mouse Rhox-13. Species sequence homology: rat.
References
1. Maclean, JA. et al. Cell. 120:369-382 (2005). 2. Geyer, CB. et al. Gene. 423:194-200 (2008).
USBio References
No references available
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